Chemical alteration of an agent (drug) that occurs by virtue of the sojourn of the agent in a biological system.
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Multiple Choice Question
_______ is expressed in both the intestinal epithelium and the kidney.
Explanation:
CYP3A4 is involved in the metabolism of
majority of drugs and is also expressed
extrahepatically. In fact, poor bioavailability of
many drugs is attributed to the drug metabolism
by CYP3A4 in gastrointestinal tract.
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