Pharmacology revision notes, some basic points from general pharmacology, pharmacology one liners, for pharmacy exams.
Revision of Pharmacology, some basic points (one liners)
1
binding of Morphine and Naloxone to the Opioid receptors
competitive antagonism
2
When both agonist and antagonist binds reversibly on the same site of the receptor
competitive antagonism
3
Antagonist binds with the same receptor as the agonist and inhibits its effect
receptor anatgonism
4
When two drugs act at different receptors or by different machanisms on the same physiological system and produce opposite effect
Functional antagonism i.e insulin and glucagon on blood sugar
5
Use of dimecaprol in arsenic poisoning is an example of
Chemical antagonism
6
Adsorption of alkaloids by activated charcoal is an example of
Physical antagonism
7
When the effect of one drug is decreased or abolished in the presence of another drug
Drug antagonism
8
When two or more drugs on simultaneous administration show effect greater than that of either drug alone
Synergism (e.g. Sulphamethoxazole + trimethoprim)
9
The enhancement of action of one drug by another inactive drug
Potentiation (supra-additive effect)
10
the range of concentration of drug which produces desired response with minimal toxicity
Therapeutic window
11
The amount of drug required to produced a desired response is called
Drug potency
12
The combined effect of two or more drugs is equal to the sum of their indivisual effect
Additive effect i.e paracetamol + ibuprofen as analgesics
