In the presence of peptides, a copper (ii) ion forms violet coloured complexes in alkali solutions.
Q2. Which is the smallest amino acid?
A) Glycine
B) Alanine
C) Valine
D) Phenylalanine
Answer: (A) Glycine
Glycine is the smallest amino acid with only 'H' as the residue.
Q3. Vitamin A is related to:
A) β-ionone
B) α-ionone
C) δ-ionone
D) ɣ-ionone
Answer: (A) β-ionone
Vitamin A is composed of β -ionone ring (cyclohexenyl) to which polyisoprenoid side chain is attached.
Q4. Vitamins that bind to Ca++ ATPase in intestinal cells is:
A) Vitamin B1
B) Vitamin B2
C) Vitamin B6
D) Vitamin D
Answer: (D) Vitamin D
Vitamin D is fat soluble responsible for enhancing intestinal absoption of calcium, Iron, Magnesium, Phosphate and zinc.
Q5. Regular use of isoniazid as antitubercular drug causes deficiency of:
A) Vitamin B2
B) vitamin B6
C) Vitamin B12
D) Vitamin B1
Answer: (B) vitamin B6
Isoniazid causes depletion of vitamin B6 (Pyridoxin).
Q6. Sakaguchi's test is specified to:
A) Glycine
B) Arginine
C) Tryptophan
D) Tyrosine
Answer: (B) Arginine
Sakaguch's test is used to detect the Arginine in proteins. The guanidine group in arginine reacts with sakaguch's reagent to form red coloured complex.
Q7. Which Enzyme is useful for the clinical diagnosis of acute pancreatitis?
A) Lipase
B) Amylase
C) Creatinine phosphokinase
D) Both A and B
Answer: (D) Both A and B
Acute pancreatitis is sudden swelling and inflammation of the pancreas. It is due to the billiary tract disease, heavy alcohol, idiopathic causes.
Q8. Which enzyme catalyse the linking of two compounds?
A) Transferase
B) Isomerase
C) Ligase
D) Lyases
Answer: (C) Ligase
Ligase is an enzyme that can catalyse the joining of two large molecules by forming a chemical bond.
Q9. Enzyme Reaction kinetics are governed by:
A) Michaelis theory
B) Menten theory
C) Michaellis and Menten theory
D) Noyes and Whitney theory
Answer: (C) Michaellis and Menten theory
Mechellis and Menten theory is one of the best models of enzyme kinetics. The models take the form of an equation describing the rate of enzymatic reaction , relating reaction rate, concentration of the substrate.
Q10. What is the source of carbon atoms in Cholesterol?
A) Acetyl-CoA
B) Lanosterol
C) Squalene
D) Mevalonic acid
Answer: (A) Acetyl-CoA
Acetyl-CoA is an important molecule in metabolism used in many biochemical reactions.
Q11. The Enzymes of HMP pathway are located in:
A) Cytosol
B) Adipose tissue
C) Heart
D) Intestine
Answer: (A) Cytosol
Cytosol is the liquid found inside cells. It is seprated into compartment by membranes. For example Mitochondrial matrix, seprates the mitochondrion into many compartments.
Q12. The citrate is converted into isocitrate via cis-aconitase by the enzyme:
A) Cutrate synthase
B) aconitase
C) isocitrate dehydrogenate
D) malate dehydrogenase
Answer: (B) aconitase
Aconitase is an enzyme that catalyse the sterio-specific isomerisation of citrate to isocitrate in the tricarboxylic acid cycle
Q13. In Glycolysis under anaerobic condition, there is a net gain of:
A) 4 ATP
B) 3 ATP
C) 2 ATP
D) 1 ATP
Answer: (C) 2 ATP
Q14. Which is the major pathway/cycle for removal of amonia in brain?
A) Glutamine pathway
B) Kreb's Henseleit cycle
C) Urea synthesis pathway
D) None of these
Answer: (A) Glutamine pathway
Q15. The disease albinism is related to:
A) defect of tyrosine metabolism
B) defect of phenylealanine metabolism
C) defect related to melanin biosynthesis
D) All of these
Answer: (C) defect related to melanin biosynthesis
Albinism is the rare group of genetic desorder that causes the skin, hair, eyes to have little or no colour.
Q16. Knoop's beta oxidation is related to:
A) oxidation of fatty acids
B) oxidation of acetyl Coenzyme
C) oxidation of keto-bodies
D) oxidation of uric acid
Answer: (A) oxidation of fatty acids
Q17. The normal level of calcium in blood plasma is:
A) 20-40 mg/ 100ml
B) 30-40 mg/100 ml
C) 9-11 mg/100 ml
D) 100mg/100 ml
Answer: (C) 9-11 mg/100 ml
the calcium is present plasma of blood in concentration of 9 to 11mg per 100ml
Q18. Xanthine oxidase contains:
A) Zinc
B) Molybdenum
C) cobalt
D) magnesium
Answer: (B) Molybdenum
Q19. Barfoed's reagent is a solution of:
A) copper sulphate
B) copper acetate in acetic acid
C) cupric tartrate
D) cupric nitrate
Answer: (B) copper acetate in acetic acid
Barfoed's reagent is used for detection of monosachrides in carbohydrate, based on the reaction of copper acetate to copper oxide. RCH + 2Cu2+ + 2 H2O → RCOOH + 2Cu2O + NH+
Q20. The risk factor for atherosclerosis is related to:
A) Chylomicron
B) VLDL
C) HDL
D) VLDL and LDL
Answer: (D) VLDL and LDL
LDL diposits excess cholesterol in the walls of blood vessels, so it is also called bad cholesterol.
Q21. The precursor for Vitamin D is:
A) Fatty acid
B) Sterol
C) Cholesterol
D) Lipid
Answer: (C) Cholesterol
Several forms of vitamin D exists. The two major forms are vitamin D2 or ergocalciferol and vitamin D3 or Cholecalciferol.
Q22. Glutathione is:
A) Dipeptide
B) Tripeptide
C) Cyclic peptide
D) Polypeptide
Answer: (B) Tripeptide
Glutathione is an important anti-oxidant in plants, animals, fungi and some bacteria. It is a tripeptide with a gamma peptide linkage between the carboxyl groups.
Q23. Bial's Reagent is a solution of:
A) Alpha napthol in alcohol
B) Phenol in 30% HCL
C) Orcinol in 30% HCL
D) Orcinol in 30% HCL + ferric chloride
Answer: (D) Orcinol in 30% HCL + ferric chloride
Bial's test is achemical test for the presence of pentose. It contains 0.4 g of orcinol, 200ml of conc. HCL and 0.5 m of 10% solution of ferric chloride.
Q24. Fluorosis is caused by the excess intake of:
A) Copper
B) Calcium
C) Zinc
D) Fluorine
Answer: (D) Fluorine
It is developemental disturbance in enamel caused by excessive exposure to high concentration of fluorine intake.
Q25. Mutarotation is:
A) change in structure
B) change in cyclic structure
C) change in optical rotation
D) none of above
Answer: (C) change in optical rotation
Mutarotation is the change in the optical rotation that occurs by epimerization. The optical rotation of the solution depends on the optical rotation of each anomer and their ratio in the solution.
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