1

Name the five vitamins required by pyruvate dehydrogenase or -ketoglutarate dehydrogenase complex

Thiamine, riboflavin, lipoic acid, niacin, pantothenic acid,

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2

Muscle glycogen does not directly contribute to blood glucose due to absence of the enyme

Absence of glucose 6-phosphatase

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3

Ascorbic acid is not synthesized in man due to lack of the enzyme

L-Gulonolactone oxidase

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4

The compound implicated in the development of cataract in diabetic patients is

Sorbitol

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5

Galactosemia is mostly due to the deficiency of the enzyme

Galactose 1-phosphate uridyltransferase

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6

The two amino acids that are never glucogenic are

Leucine and lysine

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7

Substrate level phosphorylation in citric acid cycle is catalysed by the enzyme

Succinate thiokinase

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8

The metabolic pathway concerned with the conversion of L-xylulose to D-xylulose is

Uronic acid pathway

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9

The name of the protein that has been identified to serve as a primer for glycogen synthesis is

Glycogenin

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10

The metabolite among the citric acid cycle intermediates performing a catalytic role

Oxaloacetate

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11

Which enzymes in glycolysis catalyses an irreversible reaction

Pyruvate kinase , Phosphofructokinase, Hexokinase

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12

Synthesis of 2, 3-bisphosphoglycerate occurs in the tissue namely.

Erythrocytes

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13

The hormone that lowers cAMP concentration in liver cells is

Insulin

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14

The number of ATP produced when a molecule of acetyl CoA is oxidized through citric acid cycle

12

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15

The connecting link between HMP shunt and lipid synthesis is

NADPH

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