1

Chemically modified form of a pharmacologically active compound that has to undergo biochemical or chemical transformation before exhibiting its pharmacological effect.

prodrug

1

Chemically modified form of a pharmacologically active compound that has to undergo biochemical or chemical transformation before exhibiting its pharmacological effect.

prodrug

2

Process that differentiates or separates solid particles according to their size using a meshed or perfo- rated device.

sieving

2

Process that differentiates or separates solid particles according to their size using a meshed or perfo- rated device.

sieving

3

Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.

pseudopolymorph

3

Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.

pseudopolymorph

4

Method by which powder particles are compressed into a large tablet, called a slug, which is subse- quently dry-screened and compressed into a tablet.

slugging

4

Method by which powder particles are compressed into a large tablet, called a slug, which is subse- quently dry-screened and compressed into a tablet.

slugging

5

Measure of the fraction of a given drug that is absorbed intact into the systemic circulation from a dosage form, relative to a recognized, clinically proven, standard dosage form of that drug.

relative bioavailability

5

Measure of the fraction of a given drug that is absorbed intact into the systemic circulation from a dosage form, relative to a recognized, clinically proven, standard dosage form of that drug.

relative bioavailability

6

A fluid colloidal dispersion of a solid in a liquid.


sol

6

A fluid colloidal dispersion of a solid in a liquid.


sol

7

Dosage form, semi-solid, used for the administration of drugs via the rectal route, for systemic or local effect.

7

Dosage form, semi-solid, used for the administration of drugs via the rectal route, for systemic or local effect.

8

Transition of a suspension of solid, usually colloid, particles in a liquid (sol) to an apparent solid, jelly- like material


sol-gel transition

8

Transition of a suspension of solid, usually colloid, particles in a liquid (sol) to an apparent solid, jelly- like material


sol-gel transition

9

Usually small, flat, and soft tablets, which are designed to be placed under the tongue to allow direct absorption of the active ingredient through the mucosa for systemic effect.

sublingual tablets

9

Usually small, flat, and soft tablets, which are designed to be placed under the tongue to allow direct absorption of the active ingredient through the mucosa for systemic effect.

sublingual tablets

10

Additives making a substance soluble or more soluble, especially in water.

solubilizing agents

10

Additives making a substance soluble or more soluble, especially in water.

solubilizing agents

11

Destruction or removal of microorganisms in or about an object, e.g., by steam, chemical agents (alcohol, phenol, ethylene oxide gas), high-velocity electron bombardment, gamma or ultraviolet light radiation or filtration.

sterilization

11

Destruction or removal of microorganisms in or about an object, e.g., by steam, chemical agents (alcohol, phenol, ethylene oxide gas), high-velocity electron bombardment, gamma or ultraviolet light radiation or filtration.

sterilization

12

Crystalline form of a compound in which one or more solvent molecules are part of the crystal strucure.


solvate

12

Crystalline form of a compound in which one or more solvent molecules are part of the crystal strucure.


solvate

13

Condition of being aseptic, or statistically free from living microorganisms and their spores.

sterility

13

Condition of being aseptic, or statistically free from living microorganisms and their spores.

sterility

14

Process of making dense, spherical pellets by means of special spheronizing or pelletizing equipment.

spheronization

14

Process of making dense, spherical pellets by means of special spheronizing or pelletizing equipment.

spheronization

15

Scaffold placed into narrowed, diseased vessels (mainly coronary arteries) or a device implanted in a vessel used to help keep it open.


stent

15

Scaffold placed into narrowed, diseased vessels (mainly coronary arteries) or a device implanted in a vessel used to help keep it open.


stent

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