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- physical substance in general, as distinct from mind and spirit;
- a subject or situation under consideration.
Specific case of drug embedding in insoluble excipients (typically in a polymer) in order to achieve ex- tended release.
Maximum concentration of a drug, which will form a clear solution with a given concentration of surfactant.
Concentration of a drug in the plasma, above which side effects are likely to occur in a patient.
Aggregates of colloidal dimensions (i.e., association of colloids) formed reversibly from amphiphile molecules.
Pressure-driven, membrane-based separation process in which particles and dissolved macromolecules larger than 0.1 micrometer are rejected.
Lowest concentration of an antibacterial drug necessary to inhibit the growth of a microorganism.
Release of a drug from a dosage form that it is not immediate (e.g., sustained release, retarded release, delayed-action preparations, controlled release, extended release, etc.).
Usually water or low-molecular-weight alcohols or compounds, used in topical applications and in wet granulation, for the production of tablets.
Dosage form (capsule, tablet) comprising several elements (e.g., microspheres or coated pellets) difering in the rate of drug release.
Consists of several different layers that are compressed on top of each other, to form a single tablet composed of two or more layers.