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Pharmacology

Pharmacology is the branch of medical science which deals with the mechanism, functioning, experimental analysis of impact of different drugs on living system.

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Chapters All ❱

Histamine And Antihistamine Drugs

pharmacy infoline  
30 Nov -0001   

histamine and antihistamine drugs...

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Notes All ❱

MCQs on antihistamines | medicinal chemistry | by pharmacy infoline

pharmacy infoline  
12 Jul 2021   

Antihistamines are drugs which treat rhinitis and other allergies. Typically people take antihistamines as a cheap , generic, over-the-counter medicin...

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MCQs on antihistamines | medicinal chemistry | by pharmacy infoline

pharmacy infoline  
12 Jul 2021   

Antihistamines are drugs which treat rhinitis and other allergies. Typically people take antihistamines as a cheap , generic, over-the-counter medicin...

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Commonly used drugs in Obstetric and Gynaecological conditions (starting with

prakash joshi  
5 Nov 2020   

There are some common drugs used in gynecology. Here is the list of drugs starting from "m" commonly used in obstetrics and gynecological conditio...

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Teratogenecity of drugs

solotutes  
12 Jun 2020   

Some of drugs or chemicals are fatal to embryo development. Those drugs and chemical substances which produce deviations and abnormalities in the ...

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Classification of antimicrobial drugs according to their type of action, spectrum of activity and mechanism of action

pharmacy exams  
19 May 2021   

Classification of antimicrobials is based on their type of action on microbes kill or reduce the number, spectrum of activity i.e can work on specif...

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One Liners All ❱

Pharmacist Exams revision: Pharmacology Chapter 1 - Important One Liner questions 1 of 15 〉 Continued substance use despite knowledge of having a persistent or recurrent psychological, or physical problem that is caused or exacerbated by use of the substance

Addiction

2 of 15 〉 A ligand that binds to a receptor and alters the receptor state resulting in a biological response.

Agonist

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General Pharmacology questions (one Liners)  1 of 12 〉 Adrenaline and insulin are administered through

Subcutaneous (SC) route

2 of 12 〉 In Sublingual route of drug administration Drug is absorbed through

Buccal mucosa membrane

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Revision of Pharmacology, some basic points (one liners) 1 of 12 〉 binding of Morphine and Naloxone to the Opioid receptors

competitive antagonism

2 of 12 〉 When both agonist and antagonist binds reversibly on the same site of the receptor

competitive antagonism

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Autonomic Nervous System. 1 of 3 〉 The junction of a post-ga1nglionic axonal terminal with its effector cell is termed a neuroeffector junction.

Neuroeffector junction

2 of 3 〉 Nerves that convey impulses from the brain and spinal cord (CNS) to muscles, glands and other effector organs

Efferent (Motor)

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TYPES OF CANCER 1 of 7 〉 cancer derived from germ cell which are commonly found in the brain of young ages.

Germinoma

2 of 7 〉 cancer of skin that develops when melanocytes (the cells that give the skin its tan or brown color) start to grow out of control.

Melanoma

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Hospital and Clinical Pharmacy Important Questions (one liners) 1 of 9 〉 Griseofulvin is better absorbed in

Presence of fatty meal

2 of 9 〉 Death due to cyanide poisoning results from

Inhibition of cytochrome oxidase

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Practice (MCQs) All ❱

1 of 56

Q.1 Compared to subcutaneous injection, the intramus- cular injection of drugs:

  • Is more painful
  • Produces faster response
  • Is unsuitable for depot preparations
  • Carries greater risk of anaphylactic reaction


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

2 of 56

Q.2 The majority of drugs cross biological membranes primarily by

  • Passive diffusion
  • Facilitated diffusion
  • Active transport
  • Pinocytosis


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

3 of 56

Directions:

Q.3 Which of the following drugs is most likely to be absorbed from the stomach

  • Hyoscine hydrobromide
  • Morphine sulfate
  • Diclofenac sodium
  • Quinine dihydrochloride


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

4 of 56

Directions:

Q.4 The most important factor governing absorption of a drug from intact skin is

  • Nature of the base used in the formulation
  • Lipid solubility of the drug
  • Molecular weight of the drug
  • Site of application


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

5 of 56

Q.5 Bioavailability differences among oral formulations of a drug are most likely to occur if the drug

  • Undergoes little first-pass metabolism
  • Is incompletely absorbed
  • Is freely water soluble
  • Is completely absorbed


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

6 of 56

Q.6 Marked redistribution is a feature of

  • Highly plasma protein bound drugs
  • Depot preparations
  • Highly lipid soluble drugs
  • Poorly lipid soluble drugs


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

7 of 56

Q.7 High plasma protein binding

  • Increases volume of distribution of the drug
  • Generally makes the drug long acting
  • Facilitates glomerular filtration of the drug
  • Minimises drug interactions


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

8 of 56

Q.8 Which of the following is a prodrug

  • Enalapril
  • Menapril
  • Thiazine
  • Penicillin


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

9 of 56

Q.9 Microsomal enzyme induction can be a cause of

  • Tolerance
  • Physical dependence
  • Psychological dependence
  • Idiosyncrasy


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

10 of 56

Q.10 Glomerular filtration of a drug is affected by its

  • Plasma protein binding
  • Lipid solubility
  • Degree of ionization
  • Rate of tubular secretion


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

11 of 56

Directions:

Q.1 Which of the following organs is innervated only by parasympathetic nerves

  • Sweat glands
  • Ciliary muscle
  • Iris muscles
  • Splenic capsule


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

12 of 56

Directions: .

Q.2 The following cotransmitter is most probably involved in mediating nonadrenergic-noncholinergic (NANC) relaxation of the gut

  • Nitric oxide (NO)
  • Adenosine
  • Neuropeptide Y (NPY)
  • Kallidin


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

13 of 56

Q.3 The major postjunctional cholinergic receptor is of the muscarinic type at the following site

  • Neuromuscular junction
  • Postganglionic parasympathetic
  • Adrenal medulla
  • Autonomic ganglia


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

14 of 56

Q.4 The choline ester resistant to both true and pseudo- cholinesterase is

  • Bethanechol
  • Butyrylcholine
  • Methacholine
  • Benzoylcholine


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

15 of 56

Q.5 The smooth muscle structure that is relaxed by choli- nergic drugs is

  • Colon
  • Gastric fundus
  • Bladder trigone
  • Major bronchi


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

16 of 56

Q.6 Pilocarpine is used for

  • Glaucoma
  • Paralytic ileus
  • Urinary retention
  • Infection


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

17 of 56

Q.7 The following inhibitor binds only to the ani-onic site of the cholinesterase enzyme

  • Neostigmine
  • Edrophonium
  • Physostigmine
  • Dyflos


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

18 of 56

Q.8 Reactivation of cholinesterase enzyme occurs on hydrolysis of the inhibitor by the same enzyme mole- cule in case of the following anticholinesterase

  • Edrophonium
  • Dyflos
  • Tacrine
  • Neostigmine


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

19 of 56

Q.9 Pyridostigmine differs from neostigmine in that

  • It produces less muscarinic side effects
  • It is more potent orally
  • It is longer acting
  • It does not have any direct action on NM receptor


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

20 of 56

Q.10 The site of action of miotics for therapeutic effect in angle closure glaucoma is

  • Canal of Schlemm
  • Ciliary body
  • Ciliary muscle
  • Sphincter pupillae muscle


PharmacologyD. PharmaB. PharmaBachelor of PharmacyDiploma in Pharmacy

21 of 56

Q.1 Labetalol differs from propranolol in that

  • It has additional α1 blocking property
  • It is a selective βS1 blocker
  • It does not undergo first pass metabolism
  • All of the above


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

22 of 56

Q.2 Select the β-adrenergic blocker that has additional β1blocking, vasodilator and antioxidant properties

  • Celiprolol
  • Metoprolol
  • Carvedilol
  • Acebutolol


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

23 of 56

Q.3 Select the β adrenergic blocker that is primarily eliminated unchanged by renal excretion

  • Atenolol
  • Carbinol
  • Ethanol
  • Dompirol


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

24 of 56

Q.4 Select the ultrashort acting cardioselective β adre- nergic blocker

  • Carbinol
  • Ethanol
  • Esmolol
  • Propalol


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

25 of 56

Q.5 The following disease is worsened by propranolol

  • Raynaud’s disease
  • Infection
  • Heart attack
  • Epilepsy


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

26 of 56

Q.6 Select the drug which is administered orally for erectile dysfunction in men

  • Albendazole
  • Mebendazole
  • Cocaine
  • Sildenafil


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

27 of 56

Q.7 Which of the following is a selective α1A receptor bloc- ker that affords symptomatic relief in benign prostatic hypertrophy without producing significant fall in blood pressure

  • Doxazosin
  • Alprostadil
  • Tamsulosin
  • Yohimbine


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

28 of 56

Q.8 The bladder trigone and prostatic muscles are relaxed by

  • Adrenergic α1 agonists
  • Adrenergic α1 antagonists
  • Adrenergic α2 antagonists
  • Adrenergic α2 agonists


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

29 of 56

Q.9 The drug which produces vasoconstriction despite being an α adrenergic blocker is

  • Tolazoline
  • Desmopressin
  • Ergotamine
  • Sildenafil


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

30 of 56

Q.10 While undergoing a surgical procedure a patient deve- lops hypotension. Which drug can be injected intramuscularly to raise his BP

  • Noradrenaline
  • Mephentermine
  • Isoxsuprine
  • Oxymetazoline


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

31 of 56

Q.1 Labetalol differs from propranolol in that

  • It has additional α1 blocking property
  • It is a selective βS1 blocker
  • It does not undergo first pass metabolism
  • All of the above


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

32 of 56

Q.2 Select the β-adrenergic blocker that has additional β1blocking, vasodilator and antioxidant properties

  • Celiprolol
  • Metoprolol
  • Carvedilol
  • Acebutolol


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

33 of 56

Q.3 Select the β adrenergic blocker that is primarily eliminated unchanged by renal excretion

  • Atenolol
  • Carbinol
  • Ethanol
  • Dompirol


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

34 of 56

Q.4 Select the ultrashort acting cardioselective β adre- nergic blocker

  • Carbinol
  • Ethanol
  • Esmolol
  • Propalol


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

35 of 56

Q.5 The following disease is worsened by propranolol

  • Raynaud’s disease
  • Infection
  • Heart attack
  • Epilepsy


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

36 of 56

Q.6 Select the drug which is administered orally for erectile dysfunction in men

  • Albendazole
  • Mebendazole
  • Cocaine
  • Sildenafil


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

37 of 56

Q.7 Which of the following is a selective α1A receptor bloc- ker that affords symptomatic relief in benign prostatic hypertrophy without producing significant fall in blood pressure

  • Doxazosin
  • Alprostadil
  • Tamsulosin
  • Yohimbine


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

38 of 56

Q.8 The bladder trigone and prostatic muscles are relaxed by

  • Adrenergic α1 agonists
  • Adrenergic α1 antagonists
  • Adrenergic α2 antagonists
  • Adrenergic α2 agonists


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

39 of 56

Q.9 The drug which produces vasoconstriction despite being an α adrenergic blocker is

  • Tolazoline
  • Desmopressin
  • Ergotamine
  • Sildenafil


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

40 of 56

Q.10 While undergoing a surgical procedure a patient deve- lops hypotension. Which drug can be injected intramuscularly to raise his BP

  • Noradrenaline
  • Mephentermine
  • Isoxsuprine
  • Oxymetazoline


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

41 of 56

Q.1 Labetalol differs from propranolol in that

  • It has additional α1 blocking property
  • It is a selective βS1 blocker
  • It does not undergo first pass metabolism
  • All of the above


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

42 of 56

Q.2 Select the β-adrenergic blocker that has additional β1blocking, vasodilator and antioxidant properties

  • Celiprolol
  • Metoprolol
  • Carvedilol
  • Acebutolol


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

43 of 56

Q.3 Select the β adrenergic blocker that is primarily eliminated unchanged by renal excretion

  • Atenolol
  • Carbinol
  • Ethanol
  • Dompirol


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

44 of 56

Q.4 Select the ultrashort acting cardioselective β adre- nergic blocker

  • Carbinol
  • Ethanol
  • Esmolol
  • Propalol


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

45 of 56

Q.5 The following disease is worsened by propranolol

  • Raynaud’s disease
  • Infection
  • Heart attack
  • Epilepsy


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

46 of 56

Q.6 Select the drug which is administered orally for erectile dysfunction in men

  • Albendazole
  • Mebendazole
  • Cocaine
  • Sildenafil


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

47 of 56

Q.7 Which of the following is a selective α1A receptor bloc- ker that affords symptomatic relief in benign prostatic hypertrophy without producing significant fall in blood pressure

  • Doxazosin
  • Alprostadil
  • Tamsulosin
  • Yohimbine


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

48 of 56

Q.8 The bladder trigone and prostatic muscles are relaxed by

  • Adrenergic α1 agonists
  • Adrenergic α1 antagonists
  • Adrenergic α2 antagonists
  • Adrenergic α2 agonists


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

49 of 56

Q.9 The drug which produces vasoconstriction despite being an α adrenergic blocker is

  • Tolazoline
  • Desmopressin
  • Ergotamine
  • Sildenafil


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

50 of 56

Q.10 While undergoing a surgical procedure a patient deve- lops hypotension. Which drug can be injected intramuscularly to raise his BP

  • Noradrenaline
  • Mephentermine
  • Isoxsuprine
  • Oxymetazoline


PharmacologyPharmacologyPharmacologyPost GraduationD. PharmaB. PharmaDiploma in Pharmacy

51 of 56

Q.1 The following are excreted faster in basicurine

  • Weak acids
  • Strong acids
  • Weak Bases
  • None of the above


PharmacologyB. PharmaBachelor of Pharmacy

52 of 56

Q.2 A good example of chemical antagonism

  • Heparin & Protamine
  • Protamine & Zinc
  • Heparin & Prothrombin
  • All the above


PharmacologyB. PharmaBachelor of Pharmacy

53 of 56

Q.3 Active transport differs from facilitated transport in following ways, except

  • Carrier is involved
  • It is against concentration gradient
  • Energy is required
  • All of the above


PharmacologyB. PharmaBachelor of Pharmacy

54 of 56

Q.4 Acidic drugs mainly bind to plasma

  • Albumin
  • acid glycoprotein
  • Weak acids
  • Heparin & Protamine


PharmacologyB. PharmaBachelor of Pharmacy

55 of 56

Q.5 _______ is expressed in both the intestinal epithelium and the kidney.

  • CYP378A
  • CYP4B2
  • CYP3A4
  • CYP256


PharmacologyB. PharmaBachelor of Pharmacy

56 of 56

Q.6 N-oxidation will be involved with the metabolism of following drugs, except

  • Dapsone
  • Meperidine
  • Phenytoin
  • Chlorpheniramine


PharmacologyB. PharmaBachelor of Pharmacy

Practice Tests All ❱

Pharmacology and Toxicology MCQs | Practice Test #1

Pharmacology and Toxicology MCQs | Practice Test #1
(20 Questions , 186 attempts)

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Classification of drugs in pharmacology Aptitude Test

Classification of drugs in pharmacology Aptitude Test
(30 Questions , 595 attempts)

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Pharmacology Aptitude Test

Pharmacology Aptitude Test
(10 Questions , 534 attempts)

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Test on Drugs classifications 1

Test on Drugs classifications 1
(11 Questions , 159 attempts)

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Online Practice Test for Pharmacy exams, previous Year questions

Online Practice Test for Pharmacy exams, previous Year questions
(50 Questions , 2684 attempts)

View Test

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