1

binding of Morphine and Naloxone to the Opioid receptors

competitive antagonism

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2

When both agonist and antagonist binds reversibly on the same site of the receptor

competitive antagonism

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3

Antagonist binds with the same receptor as the agonist and inhibits its effect

receptor anatgonism

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4

When two drugs act at different receptors or by different machanisms on the same physiological system and produce opposite effect

Functional antagonism i.e insulin and glucagon on blood sugar

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5

Use of dimecaprol in arsenic poisoning is an example of

Chemical antagonism

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6

Adsorption of alkaloids by activated charcoal is an example of

Physical antagonism

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7

When the effect of one drug is decreased or abolished in the presence of another drug

Drug antagonism

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8

When two or more drugs on simultaneous administration show effect greater than that of either drug alone

Synergism (e.g. Sulphamethoxazole + trimethoprim)

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9

The enhancement of action of one drug by another inactive drug

Potentiation (supra-additive effect)

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10

the range of concentration of drug which produces desired response with minimal toxicity

Therapeutic window

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11

The amount of drug required to produced a desired response is called

Drug potency

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12

The combined effect of two or more drugs is equal to the sum of their indivisual effect

Additive effect i.e paracetamol + ibuprofen as analgesics

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