An understanding of the principles of pharmacology and appropriate application to the individual older person is necessary for all those who develop, regulate, and prescribe and monitor drug therapies in older adults.
An understanding of the principles of pharmacology and appropriate application to the individual older person is necessary for all those who develop, regulate, and prescribe and monitor drug therapies in older adults.
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1 of 10
Q.1 Compared to subcutaneous injection, the intramus- cular injection of drugs:
- Is more painful
- Produces faster response
- Is unsuitable for depot preparations
- Carries greater risk of anaphylactic reaction
2 of 10
Q.2 The majority of drugs cross biological membranes primarily by
- Passive diffusion
- Facilitated diffusion
- Active transport
- Pinocytosis
Directions:
3 of 10
Q.3 Which of the following drugs is most likely to be absorbed from the stomach
- Hyoscine hydrobromide
- Morphine sulfate
- Diclofenac sodium
- Quinine dihydrochloride
4 of 10
Q.4 The most important factor governing absorption of a drug from intact skin is
- Nature of the base used in the formulation
- Lipid solubility of the drug
- Molecular weight of the drug
- Site of application
5 of 10
Q.5 Bioavailability differences among oral formulations of a drug are most likely to occur if the drug
- Undergoes little first-pass metabolism
- Is incompletely absorbed
- Is freely water soluble
- Is completely absorbed
6 of 10
Q.6 Marked redistribution is a feature of
- Highly plasma protein bound drugs
- Depot preparations
- Highly lipid soluble drugs
- Poorly lipid soluble drugs
7 of 10
Q.7 High plasma protein binding
- Increases volume of distribution of the drug
- Generally makes the drug long acting
- Facilitates glomerular filtration of the drug
- Minimises drug interactions
8 of 10
Q.8 Which of the following is a prodrug
- Enalapril
- Menapril
- Thiazine
- Penicillin
9 of 10
Q.9 Microsomal enzyme induction can be a cause of
- Tolerance
- Physical dependence
- Psychological dependence
- Idiosyncrasy
10 of 10
Q.10 Glomerular filtration of a drug is affected by its
- Plasma protein binding
- Lipid solubility
- Degree of ionization
- Rate of tubular secretion