Generic

Drug(s) or formulation(s) of drug(s) or dosage forms, which no longer have patent protection.

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Coating

Technological process consisting of the application of a substance, which forms a layer (e.g, to protect the drug and/or the tablet, to mask taste, to control the rate of drug release (e.g., film coating, sugar coating).

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Crystalline

Term that describes a solid of regular shape and the presence of three-dimensional order on the level of atomic dimensions, for a given molecule.

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Deflocculation

Reversal of coagulation or flocculation, i.e., the dispersion of aggregates to form a stable colloidal suspension or emulsion.

Deliquescent

Substance that absorbs sufficient moisture from the atmosphere to dissolve itself.

Drug

Biologically active substance, which when biodistributed in the body is expected to modify one or more of its functions.

Drug Delivery System

Sophisticated dosage form, which, by its construction, is able to modify/control the availability of the drug substance to the body by temporal or spatial considerations.

Efflorescent

Substance that loses water to form a lower hydrate or becomes anhydrous spontaneously.

Elixir

Sweet (often colored) dilute alcohol-based, “hydroalcoholic”, liquid used in the compounding of drugs to be taken by mouth in order to improve palatability.

Injection

Delivery of a generally sterile liquid medication into the body, or a vessel, tissue, or organ via syringe and needle.

Elutriation

The process of separating the lighter particles of a powder from the heavier ones by means of an up- ward-directed stream of fluid (gas or liquid).

Emulsion

Fluid colloidal dispersion system in which liquid droplets and/or liquid crystals are dispersed in a liquid.

Micelle

Aggregates of colloidal dimensions (i.e., association of colloids) formed reversibly from amphiphile molecules.

Liniments

Liquid intended for massaging into the skin.

Lyophilic

Denotes a dispersed phase having a pronounced affinity for the dispersion medium.

Hygroscopicity

Tendency of a substance to absorb water from the atmosphere.

Lozenge

Tablet, which does not contain a disintegrant and which is sucked to dissolve in the mouth to produce either a local (e.g., antiseptic) or systemic (e.g., vitamins) effect.

Modified Release

Release of a drug from a dosage form that it is not immediate (e.g., sustained release, retarded release, delayed-action preparations, controlled release, extended release, etc.).

Multilayer Tablet

Consists of several different layers that are compressed on top of each other, to form a single tablet composed of two or more layers.

Matrix Formulation

Specific case of drug embedding in insoluble excipients (typically in a polymer) in order to achieve ex- tended release.

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