1

The total number of amino acids present in adult hemoglobin

574

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2

The oxidation of ferrous (Fe2+) iron to ferric (Fe3+) iron in hemoglobin results in the formation of a compound namely

Methemoglobin

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3

The enzyme that catalyses the formation of carbonic acid

Carbonic anhydrase

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4

Name the compound that is increased in RBC of anemic patients to facilitate the supply of O2 to the tissues

2,3-Bisphosphoglycerate

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5

Sickling of RBC in sickle-cell anemia is due to polymerization of

Deoxyhemoglobin,

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6

The disorders characterized by decreased synthesis or total absence of globin chains of hemoglobin are collectively known as

Thalassemias

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7

The intermediate of citric acid cycle that is involved in heme synthesis

Succinyl CoA

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8

The enzyme defect in acute intermittent porphyria

Uroporphyrinogen synthase I

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9

The enzyme that is regulated by feedback inhibition in heme synthesis is

δ -Aminolevulinate synthase

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10

The product formed when heme oxygenase cleaves heme

Biliverdin

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11

The characteristic red colour of hemoglobin is due to

Heme

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12

The number of heme groups present in myoglobin

1

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13

The patients of sickle-cell anemia are resistant to

Malaria

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14

The compound that facilitates the release of O2 from oxyhemoglobin

C1– , H+ , 2, 3-BPG

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15

Name the amino acid that directly participates in the synthesis of heme

Glycine

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